Envision

Envision Unparalleled NTA Performance with Advanced Design and Breakthrough Performance

Higher performance derived from an advanced optical system provides lower limit of detection, enhanced fluorescence performance and efficiency, a clear image to lessen operator dependence, and superior reproducibility. Greater ease of use comes from understanding user needs, including a built-in sample pump, sealed sample cell, bubble-free fluid transfer, and a stable optical system. The Envision was engineered to address the frustrations of researchers limited by the first generations of NTA instruments. By applying proven science and dedicated development, every aspect of the system has been improved so the analytical capabilities and the user experience are truly a generation ahead.

  • Fast Setup
  • Automated Workflow
Envision-NTA

Our Partners

Effortless Operation, Consistent Results

Software built around user workflow and automating the user dependent variables through the use of advanced technology means sample operation is a breeze, thus removing operator variables and improving throughput and repeatability even further. The built-in sample pump ensures consistent, bubble-free sample loading, repeatable flow speeds, and easy cleaning cycles through a fully automated SOP. The sealed the sample cell is proven bubble-free and easily cleaned or replaceable when needed.

  • Automated Workflow Control


    Eliminates operator variability for improved reproducibility and higher throughput

  • Smart Sample Handling


    Eliminates operator variability for improved reproducibility and higher throughput

  • Bubble Introduction


    Avoid bubble introduction or sample contamination from syringe loading.

Precision Optics for Superior Sensitivity

The Envision optical system delivers a high signal-to-noise image, enabling accurate and precise measurements across diverse sample types without background optical interference. This sharply focused imaging capability enhances sensitivity, expanding the NTA technique’s measurement range to smaller particle sizes than previously possible. Furthermore, the optical engineering is precise and reproducible, so results will be comparable between instruments and laboratories. The image quality, measurement settings, and sample results are now consistent, showing minimal variation compared to the significant discrepancies observed with other NTA instruments.

  • Delivers clear, interference-free visuals for precise particle analysis.
  • Enables detection of smaller particles beyond conventional NTA limits.
  • Ensures consistent results across different instruments and environments.
Advanced Optical Design

Struggling with Inconsistent Nanoparticle Measurements?

Traditional NTA instruments often force a compromise between sensitivity, reproducibility, and ease of use. Envision removes those compromises.

The Problem

  • Automated Workflow Control


    Eliminates operator variability for improved reproducibility and higher throughput

  • Poor reproducibility


    High variance between identical samples ruins data confidence.

  • Operator-dependent variability


    Different users get different results due to manual focus and settings.

  • Limited detection range


    Inability to measure highly polydisperse samples accurately.

The Envision Solution

  • Advanced optical system


    Proprietary lasers and optics detect particles down to 10nm clearly.

  • High signal-to-noise detection


    Dramatically improves tracking accuracy across all particle types.

  • Fully automated workflow


    Auto-focus and auto-settings ensure consistent results, regardless of user.

  • Wide dynamic range


    Measure complex, polydisperse mixtures in a single automated run.

Detect the Smallest Particles with Unmatched Sensitivity

Advanced imaging and an exceptional signal-to-noise ratio enable detection of particles smaller than previously achievable with NTA. While the lower size limit depends on particle refractive index, ultra-low image noise ensures precise tracking of even weakly scattering particles.

This heightened sensitivity allows accurate measurement across the full size range of extracellular vesicles (EVs) and exosomes, as well as smaller liposomes, drug delivery nanoparticles, and viruses that are often beyond the reach of conventional systems.

Fluorescence Stability

The high sensitivity of the optical system allows the use of significantly lower laser intensity, even for the smallest and dimmest particles, resulting in improved stability of photo-sensitive fluorescent labels. By reducing laser exposure during fluorescence-mode NTA measurements, photobleaching is minimized.

Reproducibility and Repeatability

Comparative analysis of Lipid Nanoparticles before and after stress testing, highlighting the detection of larger aggregates.

Extended Dynamic Range

Rapid and precise measurement of viral concentration and aggregation state, essential for vaccine development and quality control.

See What Others Miss:Nano Resolution, Perfected

It’s time to ask: are you seeing the full picture of your exosome population? Traditional NTA tools routinely overlook exosomes smaller than 70nm, missing a vital part that defines the real biological impact.

Precision and Accuracy in Practice: A real example of how standard NTA and Evision instruments resolve mixed 55 nm and 250nm particles.

Versatility Across Applications

One powerful instrument to support your diverse research needs.

Extracellular Vesicles (EVs) & Exosomes

Accurately size and count EVs even in complex mixtures. High-sensitivity fluorescence mode for detecting specific sub-populations.

Virus & Vaccine Development

Monitor viral titer and assess aggregation rapidly. Essential for quality control in viral vector manufacturing (AAV, Lentivirus).

Lipid Nanoparticles (LNPs)

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How Envision Compares

See why leading labs are upgrading from legacy systems.

Feature

Detection Limit (size)

Concentration reproducibility

Cleaning efficiency

Sample Throughput

Envision

30nm PSL

High

Fast flush and reliable

High, consistent

Typical NTA Instruments

40-60nm PSL

Variable

Frequent and time consuming

Inconsistent, yielding lower throughput